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As the name suggests, Single stage gas regulators work in one stage to reduce the pressure leaving the cylinder through an outlet. When noting the differences between Single stage and Multi stage, it is also important to know about droop and supply pressure effect. Droop is used to describe the difference between zero pressure and the maximum amount of flow capacity in the gas regulator. Supply pressure effect, or dependency, is the variation in outlet pressure and the inlet pressure changes, or in simpler terms, occurs when the pressure changes as the cylinder empties.
Single stage regulators are recommended for uses where there will be less fluctuation in pressure or where readjustments of pressure are not an issue.